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Mutations for the autosomal recessive and autosomal dominant forms of polycystic kidney disease are not allelic

✍ Scribed by Michèle Ramsay; Stephen T. Reeders; Peter D. Thomson; Lawrence S. Milner; L. Lazarou; Thomas M. Barratt; Adrian Yau; Ordan J. Lehmann; Trefor Jenkins

Publisher
Springer
Year
1988
Tongue
English
Weight
278 KB
Volume
79
Category
Article
ISSN
0340-6717

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✦ Synopsis

The autosomal dominant form of polycystic kidney disease (ADPKD) has been linked to the alpha-globin gene locus on 16p. Linkage studies between the autosomal recessive type (ARPKD) and the 3' HVR of the alpha-globin gene cluster showed that the ARPKD and ADPKD are not allelic.

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