Selective reduction of α-keto esters with organotin hydrides application to asymmetric syntheses
✍ Scribed by A. Rahm; M. Pereyre
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 249 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0037-9646
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## Abstract We report on the development of a whole‐cell biocatalytic system based on the popular host __Saccharomyces cerevisiae__ that shows programmable performance and good atom economy in the reduction of α‐keto ester substrates. The NADPH‐dependent yeast reductase background was suppressed th
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