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Selective Reduction of Aromatic Nitro Groups in the Presence of Amide Functionality.

โœ Scribed by Dibakar Chandra Deka; Hari Sankar Kakati


Publisher
John Wiley and Sons
Year
2006
Weight
19 KB
Volume
37
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Selective Reduction
โœ Byung H. Lee; Michael F. Clothier ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 2 views

Selective Reduction of Secondary Amides to Amines in the Presence of Tertiary Amides. -The transformation is achieved by reduction of secondary amide moieties bearing an activating Cbz group with hydrides. Catalytic hydrogenation of the resulting hemiacetals removes the hydroxyl and the Cbz group t