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Selective Oxidation of Unactivated 5β C-H Bonds in Steroids by Dimethyldioxirane

✍ Scribed by Dixon, John T.; Holzapfel, Cedric W.; van Heerden, Fanie R.


Book ID
120182761
Publisher
Taylor and Francis Group
Year
1993
Tongue
English
Weight
280 KB
Volume
23
Category
Article
ISSN
0039-7911

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Cr03 in CH2C12/CH3COOH/(CH3CO)20 oxidizes hydrocarbons to alcohols and ketones, Sa-androstane and 36-acetoxy-5a-androstane are converted to 5a-androst-14-en-16-ones. Regioselective oxidations of C-H bonds are desirable for the economic ' J.