Optimized selective N-methylation of pep
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Eric Biron; Jayanta Chatterjee; Horst Kessler
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Article
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2006
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John Wiley and Sons
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English
β 169 KB
Peptides containing N(alpha)-methylamino acids exhibit interesting therapeutic profiles and are increasingly recognized as potentially useful therapeutics. Unfortunately, their synthesis is hampered by the high price and nonavailability of many N(alpha)-methylamino acids. An efficient and practical