๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

N-methylation of peptides

โœ Scribed by Marino, G.; Valente, L.; Johnstone, R. A. W.; Mohammedi-Tabrizi, F.; Sodini, G. C.


Book ID
121365230
Publisher
The Royal Society of Chemistry
Year
1972
Tongue
English
Weight
182 KB
Volume
6
Category
Article
ISSN
0022-4936

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


N-Methyl peptides
โœ VITOUX, BERNARD ;AUBRY, ANDRE ;CUNG, MANH THONG ;MARRAUD, MICHEL ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Wiley (Blackwell Publishing) ๐ŸŒ English โš– 883 KB
N-METHYL PEPTIDES.
โœ AUBRY, A. ;VITOUX, B. ;BOUSSARD, G. ;MARRAUD, M. ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Wiley (Blackwell Publishing) ๐ŸŒ English โš– 422 KB
The effect of N-methylation on helical p
โœ Chi-Fon Chang; Micheal H. Zehfus ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 632 KB

In N-methyl amino acids, the hydrogen of the N-H group is replaced with a bulky methyl group. While this change is expected to destabilize helical structures, the amount of destabilization is not known. Here the N-methyl group is placed into several positions of the helical peptides, acetyl-WGG( EAA

Optimized selective N-methylation of pep
โœ Eric Biron; Jayanta Chatterjee; Horst Kessler ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 169 KB

Peptides containing N(alpha)-methylamino acids exhibit interesting therapeutic profiles and are increasingly recognized as potentially useful therapeutics. Unfortunately, their synthesis is hampered by the high price and nonavailability of many N(alpha)-methylamino acids. An efficient and practical