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Selective Nucleic Acid Capture with Shielded Covalent Probes

✍ Scribed by Vieregg, Jeffrey; Pierce, Niles A.

Book ID
123292262
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
40 KB
Volume
106
Category
Article
ISSN
0006-3495

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Oligodeoxyribonucleotide (ODN)/polymer conjugates were obtained by covalent immobilization of various nucleic acid sequences to three different polymers. Two of them bore active ester groups for the covalent linkage via the formation of amide bonds and the third one featured aldehyde moieties for im