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Selective NR1/2B N -Methyl- d -aspartate Receptor Antagonists among Indole-2-carboxamides and Benzimidazole-2-carboxamides

✍ Scribed by Borza, István; Bozó, Éva; Barta-Szalai, Gizella; Kiss, Csilla; Tárkányi, Gábor; Demeter, Ádám; Gáti, Tamás; Háda, Viktor; Kolok, Sándor; Gere, Anikó; Fodor, László; Nagy, József; Galgóczy, Kornél; Magdó, Ildikó; Ágai, Béla; Fetter, József; Bertha, Ferenc; Keserü, György M.; Horváth, Csilla; Farkas, Sándor; Greiner, István; Domány, György


Book ID
119976675
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
319 KB
Volume
50
Category
Article
ISSN
0022-2623

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Indole-2-carboxamides as novel NR2B sele
✍ István Borza; Sándor Kolok; Anikó Gere; Éva Ágai-Csongor; Béla Ágai; Gábor Tárká 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 136 KB

A novel series of indole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of the number and position of OH groups on the indole skeleton as well as the substitution of the piperidine ring on the biological activity of the compounds was