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Selective N-alkylation of amines using nitriles under hydrogenation conditions: facile synthesis of secondary and tertiary amines

โœ Scribed by Ikawa, Takashi ;Fujita, Yuki ;Mizusaki, Tomoteru ;Betsuin, Sae ;Takamatsu, Haruki ;Maegawa, Tomohiro ;Monguchi, Yasunari ;Sajiki, Hironao


Book ID
118141708
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
313 KB
Volume
10
Category
Article
ISSN
1477-0520

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Selective one-pot synthesis of secondary
โœ Thorsten Rische; Peter Eilbracht ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 521 KB

Secondary and tertiary amines are selectively prepared in high yields by a one-pot reduction / multiple alkylation procedure from aromatic nitro compounds with styrenes, cyclic olefins or heterofunctionalised olefins, carbon monoxide and hydrogen in the presence of [Rh(cod)CIL as catalyst.