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Selective microglial activation in the rat rotenone model of Parkinson's disease

✍ Scribed by Todd B. Sherer; Ranjita Betarbet; Jin-Ho Kim; J.Timothy Greenamyre

Book ID
117473701
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
456 KB
Volume
341
Category
Article
ISSN
0304-3940

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## Abstract Parkinson's disease (PD) is characterized pathologically by progressive neurodegeneration of the nigrostriatal dopamine (DA) system. Currently, the cause of the disease is unknown, except for a small percentage of familial cases (<10% of total). The rat rotenone model reproduces many of