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Selective Interaction of Protein Kinase FA/Glycogen Synthase Kinase-3α with Membrane Phospholipids

✍ Scribed by Jau-Song Yu; Wen-Hsiung Chan; Shiaw-Der Yang


Book ID
115580725
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
496 KB
Volume
237
Category
Article
ISSN
0006-291X

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Modulation of protein kinase FA/glycogen synthase kinase-3a (kinase FA/GSK-3a) by reversible tyrosine phosphorylation/dephosphorylation was investigated. In addition to genistein, other protein tyrosine kinase (PTK) inhibitors, such as tyrphostin A47 and B42, also could induce tyrosine dephosphoryla