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Selective inhibitory effects of 4-hydroperoxycyclophosphamide (4-HCY) on T and B functions in man

✍ Scribed by H. Kodo; C. Brautbar; M. Colvin; R.P. Gale; B. Bonavida

Book ID
103624113
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
75 KB
Volume
4
Category
Article
ISSN
0192-0561

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## Abstract NF‐κB1‐dependent signaling directs the development of CD4^+^ Th2 cells during allergic airway inflammation and protective responses to helminth infection. Here, we show that IL‐4 and IL‐13 production is NF‐κB1‐dependent in mouse OVA‐specific CD4^+^ (OTII) T cells responding to alum‐prec