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Effects of NYGGF4 knockdown on insulin sensitivity and mitochondrial function in 3T3-L1 adipocytes

✍ Scribed by Chun-Mei Zhang; Xue-Qi Zeng; Rong Zhang; Chen-Bo Ji; Mei-Ling Tong; Xia Chi; Xi-Ling Li; Jia-Zheng Dai; Min Zhang; Yan Cui; Xi-Rong Guo


Publisher
Springer US
Year
2010
Tongue
English
Weight
260 KB
Volume
42
Category
Article
ISSN
0145-479X

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## Abstract PPARΞ³ plays a key role in adipocyte specific gene expression. In this study, we assessed the effects of phorbol ester (TPA)‐sensitive PKC (c/nPKC) activation on the expression of adipocyte specific genes and inflammation related genes. Treatment with both TPA and TNFΞ± decreased mRNA lev