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Selective inhibition of the C5a chemotactic cofactor function of the Vitamin D binding protein by 1,25(OH)2 Vitamin D3

✍ Scribed by Anisha B. Shah; Stephen J. DiMartino; Glenda Trujillo; Richard R. Kew


Book ID
116755701
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
216 KB
Volume
43
Category
Article
ISSN
0161-5890

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## Abstract Inducible cyclooxygenase‐2 (COX‐2) has been implicated to play a role in inflammation and carcinogenesis and selective COX‐2 inhibitors have been considered as anti‐inflammatory and cancer chemopreventive agents. 1Ξ±,25‐dihydroxyvitamin D~3~ (1Ξ±,25(OH)~2~D~3~), the active hormonal form o