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Selective inhibition of rat mesangial cell proliferation by a synthetic peptide derived from the sequence of the C2 region of PKCβ

✍ Scribed by Hsiao-Ling Wu; Christine Albrightson; Ponnal Nambi


Book ID
117409371
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
129 KB
Volume
20
Category
Article
ISSN
0196-9781

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S100B(ββ) inhibits the protein kinase C-
✍ Paul T. Wilder; Richard R. Rustandi; Alexander C. Drohat; David J. Weber 📂 Article 📅 1998 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 509 KB

## Abstract S100B(ββ) is a dimeric Ca^2+^‐binding protein that is known to inhibit the protein kinase C (PKC)‐dependent phosphorylation of several proteins. To further characterize this inhibition, we synthesized peptides based on the PKC phosphorylation domains of p53 (residues 367‐388), neuromodu