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Selective inhibition of prostaglandin synthetase by a bicyclo[2.2.1]heptene derivative

✍ Scribed by Corey, E. J.; Wlodawer, Paulina; Samuelsson, Bengt; Albonico, Sem M.


Book ID
125967593
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
245 KB
Volume
93
Category
Article
ISSN
0002-7863

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A study of isatinylidene derivatives (I) as the dienophile component of a Diels-Alder reaction was undertaken with the object of obtaining spirooxindole derivatives of the type (II) of value in the synthesis of alkaloids of the Gelsemium species. No previous synthesis of this nature appears to have