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Inhibitors of prostaglandin biosynthesis. A bicyclo-[2.2.1]-heptene analogue of ‘2’ series prostaglandins and related derivatives

✍ Scribed by Timothy J. Leeney; Peter R. Marsham; Graham A.F. Ritchie; Michael W. Senior


Book ID
119048128
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
217 KB
Volume
11
Category
Article
ISSN
0090-6980

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A Synthesis of spiro[oxindole-3,2′-bicyc
✍ C.G. Richards; M.S.F. Ross 📂 Article 📅 1968 🏛 Elsevier Science 🌐 French ⚖ 160 KB

A study of isatinylidene derivatives (I) as the dienophile component of a Diels-Alder reaction was undertaken with the object of obtaining spirooxindole derivatives of the type (II) of value in the synthesis of alkaloids of the Gelsemium species. No previous synthesis of this nature appears to have