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Selective inhibition of cyclooxygenase-2 inhibits growth and induces apoptosis in human esophageal adenocarcinoma cells

โœ Scribed by Souza, Rhonda F.; Shewmake, Kenneth; Beer, David G.; Cryer, Byron; Spechler, Stuart J.


Book ID
122926964
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
167 KB
Volume
118
Category
Article
ISSN
0016-5085

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Selective cyclooxygenase-2 inhibition su
โœ Mark Baguma-Nibasheka; Christie Barclay; Audrey W. Li; Laurette Geldenhuys; Geof ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 345 KB

## Abstract Inhibition of cyclooxygenase (COX)โ€2 is reported to suppress growth and induce apoptosis in human esophageal adenocarcinoma (EADC) cells, although the precise biologic mechanism is unclear. In this study we tested the hypothesis that the antitumor activity of COXโ€2 inhibitors may involv