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Selective inhibition of antigen-induced “step one” in cytotoxic T lymphocytes by anti-Lyt-2 antibodies

✍ Scribed by Martin Gullberg; Eva-Lotta Larsson


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
627 KB
Volume
12
Category
Article
ISSN
0014-2980

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The proliferation of autologous tumor-reactive cytotoxic T lymphocytes (CTL), induced by autologous mixed lymphocyte tumor-cell culture, was remarkably enhanced by activation with immobilized anti-CD3 monoclonal antibody (MAb) and interleukin-2 (IL-2), as compared with IL-2 alone. The activated CTL