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Selective Induction of Cyclin-Dependent Kinase Inhibitors and Their Roles in Cell Cycle Arrest Caused by Trichostatin A, an Inhibitor of Histone Deacetylase

✍ Scribed by YOUNG BAE KIM; MINORU YOSHIDA; SUEHARU HORINOUCHI


Book ID
111395732
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
148 KB
Volume
886
Category
Article
ISSN
0890-6564

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## Abstract ZD6474 is a vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. The present study was undertaken to investigate the direct antiproliferative effect of ZD6474 on human nasopharyngeal carcinoma (NPC) __in vitro__ and t