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Selective in Vitro Cytotoxicity of a Glycolytic Enzyme Inhibitor for Immature Lymphoid Cells

✍ Scribed by J. R. Mann; J. S. Simpson; M. W. McEvoy; J. Stuart

Book ID
114707690
Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
430 KB
Volume
23
Category
Article
ISSN
0007-1048

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Verapamil has been shown to overcome acquired drug resistance to vincristine in P388 leukemia both in vitro and in vivo. To study the selectivity of this action, the effect of addition of verapamil on the cytotoxicity of vincristine was studied using lymphocytes from eight patients with chronic lymp