Selective IgA deficiency: Analysis of Ig productionin vitro
β Scribed by Takatoshi Inoue; Hideo Okubo; Jiro Kudo; Tohru Ikuta; Kazuo Hachimine; Rumiko Shibata; Okiyuki Yoshinari; Kenji Fukada; Toshiyuki Yanase
- Book ID
- 105003369
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 821 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0271-9142
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Immunoglobulin-A deficiency (IgA-D) is the most common human Ig class deficiency with an estimated frequency of approximately 1 in 500 in the Swedish population. We investigated the immunoglobulin heavy chain constant region gene segments (IGHC) in 103 individuals with IgA-D and the immunoglobulin h
Fifty children with IgA deficiency were followed for 1 to 4 years from 1975 to 1978. Thirty-five had complete deficiency of serum IgA (< 2.5 IU/ml) and 15 partial deficiency (serum IgA below the 10th centile for age). Patients with another associated immunodeficiency, such as ataxia-telan giectasia,