Selective gene therapy for human lung adenocarcinoma by tumor-specific expression of herpes simplex virus thymidine kinase gene
โ Scribed by Zhenqiang Gao; Zhiping Gao; Tao Zhang; Xifu Liu
- Publisher
- Science in China Press (SCP)
- Year
- 1997
- Tongue
- English
- Weight
- 457 KB
- Volume
- 40
- Category
- Article
- ISSN
- 1674-7305
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
lacZ gene driven by the b-actin -based promoter. Ex-SEE EDITORIAL ON PAGE 1696. pression of the HSVtk gene by adenovirus from AFP promoter/enhancer (AdAFPtk) induced the cells sensitive to ganciclovir (GCV) in the AFP-producing cell We have developed a recombinant replication-deline efficiently, but
Human non-small cell lung cancer (NSCLC) cells were transfected with recombinant prodrug herpes simplex virus type I thymidine kinase (HSV-tk) cDNA, and the selected clones underwent apoptosis in response to induction by antiviral ganciclovir (GCV). The efficiency of GCV-induced growth inhibition an