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Selective estrogen receptor modulators (SERMs) and retinoids in breast cancer chemoprevention

✍ Scribed by JoAnne Zujewski


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
76 KB
Volume
39
Category
Article
ISSN
0893-6692

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Clinical development of estrogen modulat
✍ Julia A. Lawrence; Phyllis B. Malpas; Caroline C. Sigman; Gary J. Kelloff πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 103 KB πŸ‘ 2 views

Tamoxifen has proven to be beneficial in the chemoprevention of breast cancer in women at increased risk for the disease. Other compounds that mediate the estrogen pathway remain to be tested for clinical efficacy. The mechanism of action, efficacy, and dose response of the estrogen modulators is de