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Selective Elevation of Monomeric IgA1 in IgA Nephropathy Patients With Normal Renal Function

✍ Scribed by Peterman, Jeffrey H.; Julian, Bruce A.; Kirk, Katharine A.; Jackson, Susan


Book ID
124135200
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
644 KB
Volume
18
Category
Article
ISSN
0272-6386

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The mechanism of mesangial IgA deposition is poorly understood in IgA nephropathy (IgAN). Abnormal glycosylation of carbohydrate moieties in the hinge region of the IgA molecule has recently attracted much attention. In this report, we studied galactosylation and sialylation profiles in ΞΊand Ξ»-IgA 1