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Clinical Significance of Polymeric and Monomeric IgA Complexes in Patients With IgA Nephropathy

✍ Scribed by Hernando, Paloma; Egido, Jesús; Nicolas, Rosario de; Sancho, Jaime


Book ID
124122406
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
520 KB
Volume
8
Category
Article
ISSN
0272-6386

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The mechanism of mesangial IgA deposition is poorly understood in IgA nephropathy (IgAN). Abnormal glycosylation of carbohydrate moieties in the hinge region of the IgA molecule has recently attracted much attention. In this report, we studied galactosylation and sialylation profiles in κand λ-IgA 1