Mutations of p53 tumor-suppressor gene i
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Norifumi Naka; Yasuhiko Tomita; Hirofumi Nakanishi; Nobuhito Araki; Tadashi Hong
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Article
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1997
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John Wiley and Sons
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French
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Transgenic mice deficient for the p53 gene were reported to frequently develop angiosarcoma (AS), suggesting that alterations in the gene are associated with tumorigenesis of AS. However, little is known about genetic changes, including p53 gene alterations, in human AS because of its rarity. We ana