Selective cytotoxicity for transformed 3T3 cells
β Scribed by ROZENGURT, ENRIQUE; Po, CHANG CHIN
- Book ID
- 109699639
- Publisher
- Nature Publishing Group
- Year
- 1976
- Tongue
- English
- Weight
- 326 KB
- Volume
- 261
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/261701a0
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract We have studied the effects of tunicamycin, an inhibitor of dolichol pyrophosphateβdependent glycosylation of proteins, on the viability of transformed and nonβtransformed fibroblasts in culture. We have shown that a low concentration of tunicamycin (0.05 ΞΌg/ml or 5 Γ 10^β8^ M) is cytot
To study the relation of overall rates of protein degradation in the control of cell growth, we determined if transformation of fibroblasts to tumorigenicity affected their rates of degradation of short-and long-lived proteins. Rates of protein degradation were measured in nontumorigenic mouse Balb/
Total cellular calcium levels do not change when 3T3-4a cells stop proliferating due to serum depletion, or when serum-arrested quiescent cells are incubated for up to 44 hours in calcium-deficient medium (-10 pM Ca++). Upon stimulation with dialyzed serum cells enter S and progress through
## Abstract The components of unidirectional K influx and efflux have been investigated in the 3T3 cell and the SV40 transformed 3T3 cell in exponential and stationary growth phase. Over the cell densities used for transport experiments the 3T3 cell goes from exponential growth to density dependent