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Selective Cleavage of p-Nitrobenzyl Esters with Sodium Dithionite

✍ Scribed by Guibe-jampel, E.; Wakselman, M.


Book ID
120415513
Publisher
Taylor and Francis Group
Year
1982
Tongue
English
Weight
172 KB
Volume
12
Category
Article
ISSN
0039-7911

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## Abstract Sodium cyanide in hexamethylphosphoric triamide selectively cleaves methyl esters in the presence of ethyl esters with yields of __ca.__ 80%. The mechanism of the reaction has been investigated. It consists of nucleophilic displacement by cyanide of the carboxylate ion from the alcohol