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Selective chemotherapy in relation to the site of tumor transplantation

✍ Scribed by M. G. Donelli; R. Rosso; S. Garattini

Publisher
John Wiley and Sons
Year
1967
Tongue
French
Weight
222 KB
Volume
2
Category
Article
ISSN
0020-7136

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✦ Synopsis

Sarcoma 180 and Ehrlich carcinoma maintained in the ascitic form were transplanted subcutaneously, intraperitoneally and intracerebrally. The same tumor transplanted in different sites showed a different sensitivity to the same chemotherapeutic agent.

Cyclophosphamide and sarcolysin were active on subcutaneous and intraperitoneal, but not on the intracerebral tumors. On the other hand, I-methylnitrosourea was effective only on the tumors transplanted intracerebrally.

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