Induction of proliferation in primary resting T cells requires engagement of both the antigenspecific TCR and the co-stimulatory receptor CD28. Here we report that CD28 functions as an autonomous mitogenic receptor which is mobilized by TCR signaling through cytoskeletal rearrangement. Shortcutting
✦ LIBER ✦
Selective blockade of NF-κB by novel mutated IκBα suppresses CD3/CD28-induced activation of memory CD4+ T cells in asthma
✍ Scribed by L.-F. Zhou; M.-S. Zhang; A.-H. Hu; Z. Zhu; K.-S. Yin
- Book ID
- 110886404
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 443 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0105-4538
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Autonomous induction of proliferation, J
✍
Astrid Bischof; Toyomichi Hara; Chia-Huey Lin; Albertus D. Beyers; Thomas Hünig
📂
Article
📅
2000
🏛
John Wiley and Sons
🌐
English
⚖ 139 KB
👁 1 views
Differential regulation of p65 and c-Rel
✍
Carmen Sánchez-Valdepeñas; Carmen Punzón; Belén San-Antonio; Angel G. Martin; Ma
📂
Article
📅
2007
🏛
Elsevier Science
🌐
English
⚖ 901 KB
The NF-κB signalling pathway is involved
✍
Linda Milkova; Verena Voelcker; Inka Forstreuter; Ulrich Sack; Ulf Anderegg; Jan
📂
Article
📅
2010
🏛
John Wiley and Sons
🌐
English
⚖ 480 KB
Inhibition of the transcription factors
✍
Ping Wang; Per O. Anderson; Shangwu Chen; Kajsa M. Paulsson; Hans-Olov Sjögren;
📂
Article
📅
2001
🏛
Elsevier Science
🌐
English
⚖ 678 KB
Selective effects of NF-κB1 deficiency i
✍
Karine Serre; Elodie Mohr; Cécile Bénézech; Roger Bird; Mahmood Khan; Jorge H. C
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 878 KB
## Abstract NF‐κB1‐dependent signaling directs the development of CD4^+^ Th2 cells during allergic airway inflammation and protective responses to helminth infection. Here, we show that IL‐4 and IL‐13 production is NF‐κB1‐dependent in mouse OVA‐specific CD4^+^ (OTII) T cells responding to alum‐prec
Cyclosporin A inhibits the early phase o
✍
Susumu Nishiyama; Noriko Manabe; Yoshitsugu Kubota; Hiroaki Ohnishi; Akira Kitan
📂
Article
📅
2005
🏛
Elsevier Science
🌐
English
⚖ 264 KB