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Inhibition of the transcription factors AP-1 and NF-κB in CD4 T cells by peroxisome proliferator-activated receptor γ ligands

✍ Scribed by Ping Wang; Per O. Anderson; Shangwu Chen; Kajsa M. Paulsson; Hans-Olov Sjögren; Suling Li


Book ID
117797813
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
678 KB
Volume
1
Category
Article
ISSN
1567-5769

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## Abstract ## Objective Suppression of bone destruction is required as part of an effective therapeutic strategy for autoimmune arthritis. Although numerous antirheumatic drugs are in clinical use, little is known about whether they inhibit bone destruction by acting on activated T cells or other