𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Selective and sensitive determination of lactone and hydroxy acid forms of camptothecin and two derivatives (CPT- 11 and SN-38) by high-performance liquid chromatography with fluorescence detection

✍ Scribed by Katsuya Akimoto; Akiko Goto; Kazumi Ohya


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
353 KB
Volume
588
Category
Article
ISSN
1873-3778

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


High-Performance Liquid Chromatographic
✍ Gary Boyd; John F. Smyth; Duncan I. Jodrell; Jeffrey Cummings πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 97 KB

## Analysis of camptothecins in biologic media is hampered by chemical hydrolysis of the parent lactone (form I) to an inactive hydroxy acid (form II). A solidphase extraction (SPE) method utilizing C2 -bonded silica particles (100 mg, 1 ml) is presented for simultaneous determination of forms I a

Simple and highly sensitive determinatio
✍ Tetsuharu Iwata; Kouji Inoue; Masaru Nakamura; Masatoshi Yamaguchi πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 391 KB πŸ‘ 2 views

## Abstract A highly sensitive and simple reversed phase high performance liquid chromatographic (HPLC) method for the quantitative determination of free fatty acids in human serum is presented. The method is based on the direct derivatization of serum fatty acids with 6,7‐dimethoxy‐1‐methyl‐2(1__H