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Selection of T Lymphocytes in two Rheumatoid Arthritis Patients Defines Different T-Cell Receptor Vβ Repertoires in CD4+ and CD8+ T-Cell Subsets

✍ Scribed by Alessandra Sottini; Luisa Imberti; Alessandra Bettinardi; Cinzia Mazza; Roberto Gorla; Daniele Primi


Book ID
115621243
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
615 KB
Volume
6
Category
Article
ISSN
0896-8411

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The antigenic specificity of the majority of T lymphocytes in the peripheral blood is determined by the combination of a and p variable region chains present in the T cell receptor complex. Currently, the Vp chains are grouped into 25 families. Historically, determination of Vp usage has relied on d