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Selection of Self-Reactive T Cells in the Thymus

✍ Scribed by Stritesky, Gretta L.; Jameson, Stephen C.; Hogquist, Kristin A.


Book ID
111683164
Publisher
Annual Reviews
Year
2012
Tongue
English
Weight
798 KB
Volume
30
Category
Article
ISSN
0732-0582

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We compared T-cell proliferative responses to acetylcholine receptor (AChR) and to purified protein derivative (PPD) (of tuberculin) of hyperplastic thymus, thymoma, and blood cells from patients with myasthenia gravis (MG). Hyperplastic MG thymus cells gave significantly higher and more consistent