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Role of self peptides in T-cell development in the thymus

✍ Scribed by A.Y. Rudensky


Book ID
117576362
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
114 KB
Volume
53
Category
Article
ISSN
0753-3322

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Feedback Regulation of T Cell Developmen
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Recent findings suggest that mature T cells in the thymus may regulate the growth and differentiation of immature thymocytes. Here we use mathematical modeling and computer simulations to identify the thymocyte subsets that might serve as targets for regulation, and the processes that might be affec