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Selection of reagents for combinatorial synthesis using clique detection

✍ Scribed by Eleanor J. Gardiner; John D. Holliday; Peter Willett; David J. Wilton; Peter J. Artymiuk


Publisher
Wiley (John Wiley & Sons)
Year
1998
Tongue
English
Weight
123 KB
Volume
17
Category
Article
ISSN
1868-1743

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Diketopiperazines, which are cyclic dipeptides, are often formed by a side reaction of solid-phase peptide synthesis. Using the new "Backbone Amide Linker," this chemistry can be conveniently harnessed for the intentional preparation of diketopiperazines. These products will be useful scaffolds for