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Selection of peptides that bind to the core oligosaccharide of R-form LPS from a phage-displayed heptapeptide library

✍ Scribed by Ken Noda; Ryohei Yamasaki; Yumi Hironaka; Aiko Kitagawa


Book ID
117517142
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
320 KB
Volume
205
Category
Article
ISSN
0378-1097

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Selection of high affinity ligands to he
✍ Kok Lian Ho; Khatijah Yusoff; Heng Fong Seow; Wen Siang Tan πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 179 KB

M13 phages that display random disulfide constrained heptapeptides on their gpIII proteins were used to select for high affinity ligands to hepatitis B core antigen (HBcAg). Phages bearing the amino acid sequences C-WSFFSNI-C and C-WPFWGPW-C were isolated, and a binding assay in solution showed that