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Selection of peptides that bind to the core oligosaccharide of R-form LPS from a phage-displayed heptapeptide library

โœ Scribed by Ken Noda; Ryohei Yamasaki; Yumi Hironaka; Aiko Kitagawa


Book ID
109327235
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
318 KB
Volume
205
Category
Article
ISSN
0378-1097

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Selection of high affinity ligands to he
โœ Kok Lian Ho; Khatijah Yusoff; Heng Fong Seow; Wen Siang Tan ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 179 KB

M13 phages that display random disulfide constrained heptapeptides on their gpIII proteins were used to select for high affinity ligands to hepatitis B core antigen (HBcAg). Phages bearing the amino acid sequences C-WSFFSNI-C and C-WPFWGPW-C were isolated, and a binding assay in solution showed that