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Selection of large diversities of antiidiotypic antibody fragments by phage display

โœ Scribed by Steffen Goletz; Peter Astrup Christensen; Peter Kristensen; Dietmar Blohm; Ian Tomlinson; Greg Winter; Uwe Karsten

Book ID
115631606
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
242 KB
Volume
315
Category
Article
ISSN
0022-2836

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Strategies for selection of antibodies by phage display
โœ Andrew D Griffiths; Alexander R Duncan ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 689 KB

Phage antibody-display is rapidly maturing into a very effective tool for antibody generation. The recent development of large primary antibody libraries enables selection of antibodies against most targets in under two weeks and many of these antibodies have relatively high (nanomolar) affinities.