✦ LIBER ✦

Selection of antisense oligonucleotides based on multiple predicted target mRNA structures

✍ Scribed by Xiaochen Bo; Shaoke Lou; Daochun Sun; Wenjie Shu; Jing Yang; Shengqi Wang

Book ID: 115000246
Publisher: BioMed Central
Year: 2006
Tongue: English
Weight: 638 KB
Volume: 7
Category: Article
ISSN: 1471-2105
DOI: 10.1186/1471-2105-7-122

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Prediction of antisense oligonucleotide

Prediction of antisense oligonucleotide binding affinity to a structured RNA target

✍ S. Patrick Walton; Gregory N. Stephanopoulos; Martin L. Yarmush; Charles M. Roth 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB 👁 1 views

Antisense oligonucleotides, which act through the pairing of complementary bases to an RNA target sequence, are showing great promise in research and clinical applications. However, the selection of effective antisense oligonucleotides has proven more difficult than initially presumed. We developed

T.P.2.02 Development of antisense oligon

T.P.2.02 Development of antisense oligonucleotides for dystrophin exon skipping based on target site accessibility predicted by dynamic co-transcriptional pre-mRNA secondary structure analysis

✍ Z.A.D. Pramono; D.K.B. Wee; X. Qianbin; P.S. Lai; W.C. Yee 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 62 KB

Influence of mRNA Self-Structure on Hybr

Influence of mRNA Self-Structure on Hybridization: Computational Tools for Antisense Sequence Selection

✍ Nicola Toschi 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 274 KB

G.P.3.03 Accounting for pre-mRNA co-tran

G.P.3.03 Accounting for pre-mRNA co-transcriptional folding in selection of antisense oligonucleotide targets for induction of exon skipping in DMD

✍ K. Wee; Z. Pramono; J. Wang; K. MacDorman; W. Yee; P. Lai 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 60 KB

The influence of the target structure on

The influence of the target structure on the efficiency of alkylation of single-stranded DNA with the reactive derivatives of antisense oligonucleotides

✍ O.S. Fedorova; L.M. Podust; G.A. Maksakova; V.V. Gorn; D.G. Knorre 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 341 KB

Prediction of beta-turns at over 80% acc

Prediction of beta-turns at over 80% accuracy based on an ensemble of predicted secondary structures and multiple alignments

✍ Ce Zheng; Lukasz Kurgan 📂 Article 📅 2008 🏛 BioMed Central 🌐 English ⚖ 365 KB