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The influence of the target structure on the efficiency of alkylation of single-stranded DNA with the reactive derivatives of antisense oligonucleotides

✍ Scribed by O.S. Fedorova; L.M. Podust; G.A. Maksakova; V.V. Gorn; D.G. Knorre


Book ID
115925976
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
341 KB
Volume
302
Category
Article
ISSN
0014-5793

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## Abstract The influence of single‐strand breaks on the kinetics of the relaxation of DNA in a solution of low ionic strength has been investigated by a temperature jump method. The relaxation of DNA after a jump of 0.7 Β°C in the melting region has been monitored by measuring the extinction at 260