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Selection and recombination drive the evolution of MHC class II DRB diversity in ungulates

✍ Scribed by Schaschl, H; Wandeler, P; Suchentrunk, F; Obexer-Ruff, G; Goodman, S J

Book ID: 110040997
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 155 KB
Volume: 97
Category: Article
ISSN: 0018-067X
DOI: 10.1038/sj.hdy.6800892

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## Abstract Ample variations of the major histocompatibility complex (MHC) genes are essential for vertebrates to adapt to various environmental conditions. In this study, we investigated the genetic variations and evolutionary patterns of seven functional MHC class II genes (one DRA, two DRB, two