Sequence diversity of MHC class II DRB genes in the bank voleMyodes glareolus
✍ Scribed by Wiesław Babik; Jacek Radwan
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 120 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0001-7051
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Puumala virus (PUUV) is a hantavirus specifically harboured by the bank vole, Myodes (earlier Clethrionomys) glareolus. It causes a mild form of hemorrhagic fever with renal syndrome (HFRS) in humans, called Nephropathia epidemica (NE). The clinical severity of NE is variable among patients and depe
ranscription of major histocompatibility complex (MHC) class II genes is controlled by a number of transcription factors that interact with a set of conserved cisacting regulatory elements within the promoter region of MHC class II genes. These regulatory sequences include the W/S, X1, X2 and Y-box