Selection and Amplification of Hosts From Dynamic Combinatorial Libraries of Macrocyclic Disulfides
β Scribed by Otto, S.
- Book ID
- 115477834
- Publisher
- American Association for the Advancement of Science
- Year
- 2002
- Tongue
- English
- Weight
- 470 KB
- Volume
- 297
- Category
- Article
- ISSN
- 0036-8075
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We thank Prof. A. R. Fersht and Dr. C. M. Johnson for the use of their isothermal titration microcalorimeter and for technical assistance. We also thank Prof. J. B. F. N. Engberts for an initial gift of 4 and for stimulating discussions. We acknowledge support from the European Union (Marie Curie Fe
## Abstract Two different macrocyclic hosts are amplified and expressed by metal guests from the same dynamic combinatorial library (DCL) of oligoimines. We studied the thermodynamic template effect and the structure of the final compounds by a combination of ESIβMS, UV and NMR spectroscopy, and Xβ