Exploring the Relation between Amplification and Binding in Dynamic Combinatorial Libraries of Macrocyclic Synthetic Receptors in Water

Tailored Polymer-Supported Templates in

Tailored Polymer-Supported Templates in Dynamic Combinatorial Libraries: Simultaneous Selection, Amplification and Isolation of Synthetic Receptors

✍ Pol Besenius; Peter A. G. Cormack; Jingyuan Liu; Sijbren Otto; Jeremy K. M. Sand 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 986 KB

## Abstract The thermodynamically controlled synthesis and isolation of macrocyclic receptors from dynamic combinatorial libraries has been achieved in a single step using a polymer‐supported template. The templates were cinchona alkaloids which show interesting enantio‐ and diastereoselective mole