✦ LIBER ✦

Selected methyleugenol metabolites suppress topoisomerase I activity and diminish the DNA-damaging properties of the DNA-topoisomerase poison camptothecin in human colon carcinoma cells

✍ Scribed by Groh, Isabel Anna Maria; Schröter, Anika; Marko, Doris; Esselen, Melanie

Book ID: 122877135
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 79 KB
Volume: 221
Category: Article
ISSN: 0378-4274
DOI: 10.1016/j.toxlet.2013.05.247

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Anthocyanin-rich extracts suppress the D

Anthocyanin-rich extracts suppress the DNA-damaging effects of topoisomerase poisons in human colon cancer cells

✍ Melanie Esselen; Jessica Fritz; Melanie Hutter; Nicole Teller; Simone Baechler; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 394 KB

## Abstract **Scope:** The effect of two anthocyanin‐rich berry extracts (A, bilberry; B, red grape) on topoisomerases was investigated in a cell‐free system and in human HT29 colon carcinoma cells. In parallel, their impact on DNA integrity was determined. **Methods and results:** The berry extra

Delphinidin interferes with the DNA-dama

Delphinidin interferes with the DNA-damaging properties of the topoisomerase II poisons doxorubicin and etoposide in human colon carcinoma cells

✍ Melanie Kern; Jessica Fritz; Doris Marko 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 87 KB

Induction of DNA Damage, Inhibition of D

Induction of DNA Damage, Inhibition of DNA Synthesis, and Suppression of c-myc Expression by the Topoisomerase I Inhibitor, Camptothecin, in MCF-7 Human Breast Tumor Cells

✍ Pramod T. Jain; Frank A. Fornari; Joyce K. Randolph; Michael S. Orr; David A. Ge 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 479 KB