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Delphinidin interferes with the DNA-damaging properties of the topoisomerase II poisons doxorubicin and etoposide in human colon carcinoma cells

✍ Scribed by Melanie Kern; Jessica Fritz; Doris Marko

Book ID
119379626
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
87 KB
Volume
172
Category
Article
ISSN
0378-4274

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Anthocyanin-rich extracts suppress the D
Anthocyanin-rich extracts suppress the DNA-damaging effects of topoisomerase poisons in human colon cancer cells
✍ Melanie Esselen; Jessica Fritz; Melanie Hutter; Nicole Teller; Simone Baechler; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 394 KB

## Abstract **Scope:** The effect of two anthocyanin‐rich berry extracts (A, bilberry; B, red grape) on topoisomerases was investigated in a cell‐free system and in human HT29 colon carcinoma cells. In parallel, their impact on DNA integrity was determined. **Methods and results:** The berry extra