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Seizure susceptibility and anticonvulsant activity of carbamazepine, diphenylhydantoin and phenobarbital in rats with selective depletions of brain monoamines

✍ Scribed by A. Quattrone; V. Crunelli; R. Samanin

Book ID
118953923
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
585 KB
Volume
17
Category
Article
ISSN
0028-3908

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## Abstract The activities of catechol‐__O__‐methyl transferase (COMT), monoamine oxidase (MAO), and a methanol forming enzyme were studied in whole brain homogenates and in livers obtained from DBA/2J, C57B1/6J, and F~1~ hybrid mice. DBA/2J mice are extremely susceptible to audiogenic seizures, wh