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Segregation Analysis of Esophageal Cancer in a Moderately High–Incidence Area of Northern China

✍ Scribed by Weihua Zhang; Joan E. Bailey-Wilson; Weidong Li; Xiuqin Wang; Chunlin Zhang; Xuezheng Mao; Zhihua Liu; Chuannong Zhou; Min Wu

Book ID
117853341
Publisher
American Society of Human Genetics
Year
2000
Tongue
English
Weight
110 KB
Volume
67
Category
Article
ISSN
0002-9297

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## Carcinomas of the upper digestive tract (squamous-cell carcinoma of the esophagus, adenocarcinoma of the cardia) from 24 patients residing in Linxian (China) and near-by high-incidence areas were analyzed for mutations in exons 5-8 of the p53 tumor-suppressor gene. Mutations were identified by